Since its first descriptions nearly 200 years ago, the malady known as Charcot Arthropathy has proven enigmatic, elusive and often profoundly devastating. Clinician researchers worldwide have contributed much in recent years to understanding the pathophysiology of the disease. Now, a new approach seeks to assemble key clinical criteria into a simple classification system to predict outcome and direct therapy. To discuss this bold approach is Lee Rogers, a rising star in the field of amputation prevention. Lee was a former fellow at CLEAR and runs the Amputation Prevention Center at Broadlawns Medical Center in Des Moines, Iowa as well as serving as active CLEAR faculty at Rosalind Franklin University of Medicine and Science in Chicago.